Dr.Sutapa Mukherjee

Sutapa Mukherjee_Zoology - Sutapa Mukherjee.jpg

Dr. Sutapa Mukherjee

Assistant Professor

Email: sutapa.mukherjee@visva-bharati.ac.in

About the Faculty

Dr. Sutapa Mukherjee joined the department in the year 2012. She has obtained her masters degree () and her doctoral degree from Utkal University, Bhubaneshwar (). Before joining the department she has worked as a research associate in Maulana Abul kalam Azad University of Technology, Kolkata (2010-2012). Her research area of interest includes Biochemistry & Cellular Signaling; Endocrinology & Metabolism; Reproductive Physiology; Environmental Toxicology.

Awards and Professional Recognition

Early Career Research Award, Science and Engineering Research Board (SERB), Govt. of India, 2018-2022.
UGC-FRPS Start-Up Grant for New Faculty, University Grants Commission (UGC), Govt. of India, 2014-2016.
Research Associateship (RA-ICMR), Indian Council of Medical Research (ICMR),Govt. of India, 2011-2012.
Research Associateship (RA-CSIR-SCHEME), Council of Scientific & Industrial Research (CSIR), Govt. of India, 2010-2011.
Best Oral Presentation on „Semester System in Indian Higher Education: Is It Fulfilling Its Purpose?‟ in the National Symposium on Quality Assurance in Higher Education organized by the UGC-HRDC, Jadavpur University Salt Lake Campus, Kolkata on March 30, 2017.
Prof. N.J. Chinoy Prize for Best Oral Presentation in the XXIII National Symposium on Reproductive Biology & Comparative Endocrinology, 2005.

Current Research Activities

Exploring the molecular mechanisms involved in the pathogenesis of insulin resistance and type 2 diabetes, and its amelioration.
Evaluating the adverse effects, in particular, metabolic and reproductive toxicity from exposure to endocrine disrupting compounds, plasticizers

Titles

Year

Duration

Sanctioned Amount
(In Lakhs)

PI/Co-PI

Status

To study lipid induced changes in adipocyte antioxidant response and the role of NADPH oxidase in obesity mediated insulin resistance

2014

2 Amount

PI: Dr. Sutapa Mukherjee

Completed

To investigate whether lipid induced fetuinA from adipocytes could link insulin resistance and immunity

2014

4 Amount

PI: Dr. Sutapa Mukherjee

Completed

To elucidate the mechanisms regulating testicular germ cell apoptosis in high fat diet induced obesity leading to insulin resistance

2018

4 Amount

PI: Dr. Sutapa Mukherjee

Completed

2019

3 Amount

Assessment of endocrine disruption in fish reproduction‟ [A Multi-Institutional Project with VisvaBharati as Lead Centre in collaboration with ICAR-CIFRI, Kolkata and ICAR-CIFA, Odisha]

Co-PI: Dr. Sutapa Mukherjee

Completed

Research Publications

Mondal, S., Basu, S., Ghosh, S., Guria, S., & Mukherjee, S. (2024). Diethyl phthalate, a plasticizer, induces adipocyte inflammation and apoptosis in mice after long‐term dietary administration. Journal of Biochemical and Molecular Toxicology, 38(1), e23561.
Guria, S., Basu, S., Hoory, A., Mukherjee, S., & Mukhopadhyay, S. (2023). Inflammatory Overtones of Organokines in Metabolic Syndrome and Type 2 Diabetes. Journal of the Indian Institute of Science, 103(1), 103-121.
Guria, S., Hoory, A., Das, S., Chattopadhyay, D., & Mukherjee, S. (2023). Adipose tissue macrophages and their role in obesity-associated insulin resistance: an overview of the complex dynamics at play. Bioscience reports, 43(3), BSR20220200.
Chattopadhyay, D., Das, S., Guria, S., Basu, S., & Mukherjee, S. (2021). Fetuin-A regulates adipose tissue macrophage content and activation in insulin resistant mice through MCP-1 and iNOS: Involvement of IFNγ-JAK2-STAT1 pathway. Biochemical Journal, 478(22), 4027-4043.
Mukherjee S. Male fertility concerns during COVID-19 pandemic. J Reprod Healthc Med 2021;2(Suppl_1):S55-S8.
Das, S., Chattopadhyay, D., Chatterjee, S. K., Mondal, S. A., Majumdar, S. S., Mukhopadhyay, S., ... & Mukherjee, S. (2021). Increase in PPARγ inhibitory phosphorylation by Fetuin—A through the activation of Ras-MEK-ERK pathway causes insulin resistance. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1867(4), 166050.
Mondal, S., & Mukherjee, S. (2020). Long-term dietary administration of diethyl phthalate triggers loss of insulin sensitivity in two key insulin target tissues of mice. Human & experimental toxicology, 39(7), 984-993.
Mondal, S., Ghosh, S., Bhattacharya, S., & Mukherjee, S. (2019). Chronic dietary administration of lower levels of diethyl phthalate induces murine testicular germ cell inflammation and sperm pathologies: Involvement of oxidative stress. Chemosphere, 229, 443-451.
Ghosh, S., & Mukherjee, S. (2018). Testicular germ cell apoptosis and sperm defects in mice upon long‐term high fat diet feeding. Journal of cellular physiology, 233(10), 6896-6909.
Mukherjee, S., Das, S., Chattopadhyay, D., Sarkar, S., Chatterjee, S. K., Talukdar, D., ... & Bhattacharya, S. (2018). Attenuation of macrophage accumulation and polarisation in obese diabetic mice by a small molecule significantly improved insulin sensitivity. Biochemical and Biophysical Research Communications, 501(3), 771-778.
Chattopadhyay, M., Mukherjee, S., Chatterjee, S. K., Chattopadhyay, D., Das, S., Majumdar, S. S., ... & Bhattarcharya, S. (2018). Impairment of energy sensors, SIRT1 and AMPK, in lipid induced inflamed adipocyte is regulated by Fetuin A. Cellular signalling, 42, 67-76.
Mukherjee, S., Samanta, L., Roy, A., Bhanja, S., & Chainy, G. B. (2014). Supplementation of T3 recovers hypothyroid rat liver cells from oxidatively damaged inner mitochondrial membrane leading to apoptosis. BioMed Research International, 2014(1), 590897.
Chatterjee, P., Seal, S., Mukherjee, S., Kundu, R., Mukherjee, S., Ray, S., ... & Bhattacharya, S. (2013). Adipocyte fetuin-A contributes to macrophage migration into adipose tissue and polarization of macrophages. Journal of Biological Chemistry, 288(39), 28324-28330.
Lee, J. I., Mukherjee, S., Yoon, K. H., Dwivedi, M., & Bandyopadhyay, J. (2013). The multiple faces of calcineurin signaling in Caenorhabditis elegans: development, behaviour and aging. Journal of biosciences, 38, 417-431.
Chattopadhyay, S., Choudhury, S., Roy, A., Chainy, G. B., & Samanta, L. (2010). T3 fails to restore mitochondrial thiol redox status altered by experimental hypothyroidism in rat testis. General and Comparative Endocrinology, 169(1), 39-47.
Chattopadhyay, S., Sahoo, D. K., Roy, A., Samanta, L., & Chainy, G. B. (2010). Thiol redox status critically influences mitochondrial response to thyroid hormone‐induced hepatic oxidative injury: a temporal analysis. Cell Biochemistry and Function: Cellular biochemistry and its modulation by active agents or disease, 28(2), 126-134.
Chattopadhyay, S., Sahoo, D. K., Subudhi, U., & Chainy, G. B. N. (2007). Differential expression profiles of antioxidant enzymes and glutathione redox status in hyperthyroid rats: a temporal analysis. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology, 146(3), 383-391.
Sahoo, D. K., Roy, A., Chattopadhyay, S., & Chainy, G. B. N. (2007). Effect of T 3 treatment on glutathione redox pool and its metabolizing enzymes in mitochondrial and post-mitochondrial fractions of adult rat testes.
Chattopadhyay, S., Zaidi, G., Das, K., & Chainy, G. B. N. (2003). Effects of hypothyroidi s m induced by 6-n-propylthiouracil and its rever sa l by T 3 on rat heart s up eroxide di s muta se, catalase and lipid peroxidation.

Book Chapters

Mukherjee, S., Das, S., Chattopadhyay, D., & Mukhopadhyay, S. (2024). Obesity-mediated insulin resistance in target tissues: role of adiponectin, Fetuin-A, and Irisin. In Metabolic Syndrome (pp. 511-525). Academic Press.
Chakrobarty, P., & Mukherjee, S. (2023). Reproductive toxicity of phthalates: An inflammatory perspective. In Immunology and Reproduction: An Interlinking Paradigm ‒ ISSRF Newsletter (32nd ed., pp. 23-25). Indian Society for the Study of Reproduction and Fertility.
Basu, S., Das, P., & Mukherjee, S. (2023). Proteomics approaches in assisted reproduction: An overview. In OMICS in Reproductive Health Research ‒ ISSRF Newsletter (32nd ed., pp. 23-25). Indian Society for the Study of Reproduction and Fertility.
Mondal, S. (2019). Male factor infertility and phthalate esters. In Translational Research in Reproductive Health ‒ ISSRF Newsletter (24th ed., pp. 98-100). Indian Society for the Study of Reproduction and Fertility.
Ghosh, S., & Mukherjee, S. (2019). The link between obesity and male reproductive impairment. In Empowering Reproductive Health through Basic Research ‒ ISSRF Newsletter (23rd ed., pp. 109-111). Indian Society for the Study of Reproduction and Fertility.
Mukherjee, S. (2016). Mobile phones and Wi-Fi: Looming Threat to Male Reproductive Health. In Environmental Impacts on Reproductive Health ‒ ISSRF Newsletter (18th ed., pp. 73-76). Indian Society for the Study of Reproduction and Fertility.

Name

Year of award

Title of thesis

Current Position

Dr. Songita Ghosh

2019

Testicular impairment and oxidative status of adipose tissue in relation to insulin resistance: Amelioration through olive oil based diet

D.S. Kothari Post-
Doctoral Fellow University of Calcutta,
Kolkata, India

Dr. Shirsha Mondal

2021

Involvement of diethyl
phthalate in insulin resistance, type 2 diabetes and reproductive
impairment in male mice

Assistant Professor,
Govt. College
Dhimarkheda (Rani
Durgavati
Vishwavidyalaya),
Madhya Pradesh, India

Dr. Snehasis Das

2022

Lipid induced impairment of energy homeostasis in mice skeletal muscle and
adipose tissue during
insulin resistance

Post Doctoral Fellow
Harold Hamm Diabetes
Research Centre,
University of Oklahoma,
U.S.A.

Dr. Dipanjan
Chattopadhyay

2022

Fetuin-A induced adipose tissue inflammation and
macrophage recruitment
in obese insulin resistant
mice, and its amelioration

Research Manager – In
vitro Biology Sun Pharma Advance Research Centre, Vadodara, Gujarat, India; Presently Post Doctoral Fellow University of Oklahoma, U.S.A.

Zoology

Department of

Visva-Bharati Santiniketan

Titles

Year

Duration

Sanctioned Amount (In Lakhs)

PI/Co-PI

Status

To study lipid induced changes in adipocyte antioxidant response and the role of NADPH oxidase in obesity mediated insulin resistance

2014

2

Amount

PI: Dr. Sutapa Mukherjee

Completed

​To investigate whether lipid induced fetuinA from adipocytes could link insulin resistance and immunity

2014

4

Amount

PI: Dr. Sutapa Mukherjee

Completed

To elucidate the mechanisms regulating testicular germ cell apoptosis in high fat diet induced obesity leading to insulin resistance

2018

4

Amount

PI: Dr. Sutapa Mukherjee

Completed

2019

3

Amount

Assessment of endocrine disruption in fish reproduction‟ [A Multi-Institutional Project with VisvaBharati as Lead Centre in collaboration with ICAR-CIFRI, Kolkata and ICAR-CIFA, Odisha]

Co-PI: Dr. Sutapa Mukherjee

Completed

Visva-Bharati
Santiniketan

Sanctioned Amount
(In Lakhs)

To investigate whether lipid induced fetuinA from adipocytes could link insulin resistance and immunity